Peripheral T-Cell Lymphomas

William R. Macon

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Peripheral T-cell lymphomas (PTCLs) are malignancies of immunologically mature T-cells that arise in peripheral lymphoid tissues such as lymph nodes, spleen, gastrointestinal tract, and skin. These lymphomas are uncommon as compared with the incidence of B-cell lymphomas, and they comprise only 5% to 10% of non-Hodgkin lymphomas in North America and Western Europe. A variety of specific disease entities have been recognized among PTCLs, and they tend to have lymph node, extranodal/cutaneous, or mixed leukemic/lymphomatous presentations. Most PTCLs have an aggressive clinical course. The clinicopathologic features of the various PTCLs are described herein.

Original languageEnglish (US)
Pages (from-to)829-842
Number of pages14
JournalHematology/Oncology Clinics of North America
Issue number4
StatePublished - Aug 2009


  • Anaplastic large cell
  • Angioimmunoblastic
  • Enteropathy-associated
  • HTLV-1
  • Hepatosplenic
  • Mycosis fungoides
  • Peripheral T-cell lymphoma

ASJC Scopus subject areas

  • Hematology
  • Oncology


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