TY - JOUR
T1 - Peripheral blood progenitor cell mobilization for autologous and allogeneic hematopoietic cell transplantation
T2 - Guidelines from the american society for blood and marrow transplantation
AU - Duong, Hien K.
AU - Savani, Bipin N.
AU - Copelan, Ed
AU - Devine, Steven
AU - Costa, Luciano J.
AU - Wingard, John R.
AU - Shaughnessy, Paul
AU - Majhail, Navneet
AU - Perales, Miguel Angel
AU - Cutler, Corey S.
AU - Bensinger, William
AU - Litzow, Mark R.
AU - Mohty, Mohamad
AU - Champlin, Richard E.
AU - Leather, Helen
AU - Giralt, Sergio
AU - Carpenter, Paul A.
PY - 2014/9
Y1 - 2014/9
N2 - Peripheral blood progenitor cell mobilization practices vary significantly among institutions. Effective mobilization regimens include growth factor alone, chemotherapy and growth factor combined, and, more recently, incorporation of plerixafor with either approach. Many institutions have developed algorithms to improve stem cell mobilization success rates and cost-effectiveness. However, an optimal stem cell mobilization regimen has not been defined. Practical guidelines are needed to address important clinical questions, including which growth factor is optimal, what chemotherapy and dose is most effective, and when to initiate leukapheresis. We present recommendations, based on a comprehensive review of the literature, from the American Society of Blood and Marrow Transplantation.
AB - Peripheral blood progenitor cell mobilization practices vary significantly among institutions. Effective mobilization regimens include growth factor alone, chemotherapy and growth factor combined, and, more recently, incorporation of plerixafor with either approach. Many institutions have developed algorithms to improve stem cell mobilization success rates and cost-effectiveness. However, an optimal stem cell mobilization regimen has not been defined. Practical guidelines are needed to address important clinical questions, including which growth factor is optimal, what chemotherapy and dose is most effective, and when to initiate leukapheresis. We present recommendations, based on a comprehensive review of the literature, from the American Society of Blood and Marrow Transplantation.
KW - Hematopoietic transplantation
KW - Peripheral blood
KW - Progenitor cell mobilization
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U2 - 10.1016/j.bbmt.2014.05.003
DO - 10.1016/j.bbmt.2014.05.003
M3 - Review article
C2 - 24816581
AN - SCOPUS:84905592751
SN - 1083-8791
VL - 20
SP - 1262
EP - 1273
JO - Biology of Blood and Marrow Transplantation
JF - Biology of Blood and Marrow Transplantation
IS - 9
ER -