Perioperative complications in open versus percutaneous treatment of spinal fractures in patients with an ankylosed spine

Charbel D. Moussallem, Brandon A. McCutcheon, Michelle J. Clarke, Quanqi Cui, Bradford L. Currier, Michael J. Yaszemski, Paul M. Huddleston, Peter S. Rose, Brett Freedman, Mark B. Dekutoski, Mohamad Bydon, Ahmad Nassr

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


We compared open stabilization of vertebral fractures to percutaneous spinal fixation techniques in patients with a diagnosis of either ankylosing spondylitis (AS) or diffuse idiopathic skeletal hyperostosis (DISH). A retrospective review of patients known to have AS or DISH treated for spinal column fracture at a single institution between 1995 and 2011 was performed. Patients were analyzed by the type of fixation, divided into either a percutaneous group (PG) or an open group (OG). There were 41 patients identified with a spinal column fracture and history of AS or DISH who received surgical intervention. There were 17 (42%) patients with AS and 24 (58%) with DISH. Patients in the PG and OG cohorts presented with similar mechanisms of injury, Injury Severity Scale, number of vertebral fractures, number of additional injuries, and Arbeitsgemeinschaft für Osteosynthesefragen (AO) classification scores. Mean operative time (254.76 minutes versus 334.67 minutes, p = 0.040), estimated blood loss (166.8 versus 1240.36 mL, p < 0.001), blood transfusion volume (178.32 versus 848.69 mL, p < 0.001), and time to discharge (9.58 days versus 16.73 days, p = 0.008) were significantly less in the PG cohort. The rate of blood transfusion (36% versus 87.5%, p = 0.001) and complications (56% versus 87%, p = 0.045) were significantly less in the PG cohort. Percutaneous stabilization of fractures in patients with AS or DISH was associated with lower blood loss, shorter operative times and decreased need for transfusion, shorter hospitalization time and a lower perioperative complication rate.

Original languageEnglish (US)
Pages (from-to)88-92
Number of pages5
JournalJournal of Clinical Neuroscience
StatePublished - Aug 1 2016


  • Ankylosing spondylitis
  • Diffuse idiopathic skeletal hyperostosis
  • Open fixation
  • Percutaneous stabilization
  • Surgery

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)


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