Perineural spread of cervical cancer to the sciatic nerve

Benjamin Matthew Howe, Kimberly K. Amrami, Mark A. Nathan, Joaquin J. Garcia, Robert J. Spinner

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


In this report we present a patient with a recent diagnosis of cervical adenocarcinoma with progressive left lower extremity pain and weakness. MR imaging of the pelvis and subsequent FDG CT/PET were complementary in demonstrating abnormalities worrisome for perineural spread of malignancy, which was confirmed with an open fascicular biopsy of the sciatic nerve. We review the imaging and propose a mechanism of perineural spread to the sciatic nerve, which we believe is supported by the imaging in this case.

Original languageEnglish (US)
Pages (from-to)1627-1631
Number of pages5
JournalSkeletal Radiology
Issue number11
StatePublished - Nov 2013


  • Malignant plexopathy
  • Perineural malignancy
  • Perineural sciatic

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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