Peridevice Leak After Left Atrial Appendage Occlusion: Incidence, Mechanisms, Clinical Impact, and Management

Mohamad Alkhouli, Ole De Backer, Christopher R. Ellis, Jens Erik Nielsen-Kudsk, Horst Sievert, Andrea Natale, Dhanunjaya Lakkireddy, David R. Holmes

Research output: Contribution to journalReview articlepeer-review

Abstract

Left atrial appendage occlusion is an increasingly adopted stroke prevention strategy in patients with atrial fibrillation. However, peridevice leaks after the procedure are not infrequent and have recently been shown to confer a higher risk for subsequent ischemic events. In this paper, the authors review the available research on the frequency, mechanisms, clinical significance, and management of peridevice leak after percutaneous left atrial appendage occlusion.

Original languageEnglish (US)
Pages (from-to)627-642
Number of pages16
JournalJACC: Cardiovascular Interventions
Volume16
Issue number6
DOIs
StatePublished - Mar 27 2023

Keywords

  • anticoagulation
  • atrial fibrillation
  • left atrial appendage occlusion
  • stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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