Perflutren lipid microsphere injectable suspension for cardiac ultrasound

Sahar S. Abdelmoneim, Sharon L. Mulvagh

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Echocardiography is a widely available noninvasive procedure for diagnosing cardiovascular disease. With the development of clinically useful microbubble contrast agents to enhance echocardiographic images and advantages of portability without radiation, microbubble contrast agents have become essential established adjunctive tools to perform state-of-the-art echocardiography. Several manufacturers produce commercially available stabilized microbubbles for intravenous use. Perflutren lipid microsphere (DEFINITY®) is one of the second generation microbubble contrast agents approved for left ventricular opacification and left ventricular endocardial border detection, and is the subject of this review.

Original languageEnglish (US)
Pages (from-to)171-191
Number of pages21
JournalImaging in Medicine
Issue number2
StatePublished - Apr 2012


  • contrast echocardiography
  • endocardial border definition
  • left ventricular opacification
  • perflutren lipid microsphere
  • stress echocardiography
  • ultrasound microbubble contrast agents

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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