Perfluorocarbon liquids in the management of complicated vitreoretinal conditions

W. F. Mieler, F. Chou, E. L. Arrindell, D. P. Han, J. S. Pulido, G. W. Abrams

Research output: Contribution to journalArticlepeer-review


Purpose. To review the trends it the usage of perfluoro-n-octane (PFO) over a 3-year time frame (1991-1993), and to evaluate the surgical success rate, within specific diagnoses. Methods. One hundred seventy-two consecutive pars plana vitrectomy cases involving the use of PFO were retrospectively analyzed. Indications for usage of PFO included (1) facilitation of retinal membrane dissection, (2) redundant retina following retinal membrane dissection, (3) giant retinal tears (4) flattening of retinectomy/retinotomy, and (5) several other miscellaneous causes. Results. Over the 3-year time frame of the study, PFO was utilized in 172 of 818 vitrectomy cases (21.0%); 39 of 238 (16.4%) in 1991, 62 of 300 (20.7%) in 1992, and in 71 of 280 (25.4%) in 1993. On a percentage basis, the PFO was utilized most frequently in giant retinal tears (97%), followed by penetrating trauma (40%). proliferative vitreoretinopathy (28%), diabetic vitrectomy (11%), and miscellaneous cases (8%). Individual diagnosis specific success rates will be reviewed, though combining all diagnoses over the 3-year time span, and with follow-up of 6 months, the anatomic success rate was 83.9%. Ambulatory visual acuity (5/200 or better) was achieved in 73.2%. Conclusions. PFO proved to be an extremely useful adjunct in the management of a variety of complex vitreoretinal conditions. While the PFO facilitated intraoperative retinal reattachment, its influence on the overall surgical success rate could not be fully determined due to the non-randomized nature of the study.

Original languageEnglish (US)
Pages (from-to)S397
JournalInvestigative Ophthalmology and Visual Science
Issue number3
StatePublished - Feb 15 1996

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


Dive into the research topics of 'Perfluorocarbon liquids in the management of complicated vitreoretinal conditions'. Together they form a unique fingerprint.

Cite this