Pathophysiology of Sports-Related Concussion

Kristen Steenerson; Amaal Jilani Starling

doi:10.1016/j.ncl.2017.03.011

Pathophysiology of Sports-Related Concussion

Kristen Steenerson, Amaal Jilani Starling

Neurology

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

Concussion pathophysiology is complicated and involves numerous mechanisms, including excessive neurotransmitter release, metabolic derangements, neuroinflammation, cerebral blood flow changes, and axonal disruption. The initial biomechanical impact in a concussion results in abnormal function at the cellular level, which initiates a cascade of events that leads to microstructural changes and, in the minority of cases, more persistent, permanent damage.

Original language	English (US)
Pages (from-to)	403-408
Number of pages	6
Journal	Neurologic clinics
Volume	35
Issue number	3
DOIs	https://doi.org/10.1016/j.ncl.2017.03.011
State	Published - Aug 2017

Keywords

Concussion
TBI
Trauma
Traumatic brain injury

ASJC Scopus subject areas

Clinical Neurology

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10.1016/j.ncl.2017.03.011

Cite this

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title = "Pathophysiology of Sports-Related Concussion",

abstract = "Concussion pathophysiology is complicated and involves numerous mechanisms, including excessive neurotransmitter release, metabolic derangements, neuroinflammation, cerebral blood flow changes, and axonal disruption. The initial biomechanical impact in a concussion results in abnormal function at the cellular level, which initiates a cascade of events that leads to microstructural changes and, in the minority of cases, more persistent, permanent damage.",

keywords = "Concussion, TBI, Trauma, Traumatic brain injury",

author = "Kristen Steenerson and Starling, {Amaal Jilani}",

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year = "2017",

month = aug,

doi = "10.1016/j.ncl.2017.03.011",

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AU - Steenerson, Kristen

AU - Starling, Amaal Jilani

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AB - Concussion pathophysiology is complicated and involves numerous mechanisms, including excessive neurotransmitter release, metabolic derangements, neuroinflammation, cerebral blood flow changes, and axonal disruption. The initial biomechanical impact in a concussion results in abnormal function at the cellular level, which initiates a cascade of events that leads to microstructural changes and, in the minority of cases, more persistent, permanent damage.

KW - Concussion

KW - TBI

KW - Trauma

KW - Traumatic brain injury

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Pathophysiology of Sports-Related Concussion

Abstract

Keywords

ASJC Scopus subject areas

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