Pathophysiology of migraine & triptan mechanism of action

Rashmi B. Halker, Bert B. Vargas

Research output: Chapter in Book/Report/Conference proceedingChapter


Migraine is a disabling and highly prevalent disorder with a cumulative lifetime incidence of 7.4% in males and 21% in females [1]. Numerous advances have been made in recent years, which have helped to explain the complex pathophysiology of this disorder and have also helped to provide insight into new possibilities for treatment and prevention. These same advances have also served to legitimize migraine as a significant public health concern with true neurobiological underpinnings and environmental influences and have also provided additional insight into the possible mechanism of action of triptans.

Original languageEnglish (US)
Title of host publicationTriptans for Migraine
PublisherFuture Medicine Ltd.
Number of pages9
ISBN (Electronic)9781780840666
ISBN (Print)9781780841335
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • General Medicine


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