Paroxysmal dysphasia in a 68 year-old man: Enhancing the MRI spectrum!

Ugur Sener, William O. Tatum, Alfredo Quinones-Hinojosa, Deependra Mahato, Anteneh M. Feyissa

Research output: Contribution to journalArticlepeer-review


Brain tumor-related epilepsy is a common complication of primary and metastatic brain tumors with seizures often representing the first manifestation of the tumor. The size and location of the tumor can make detection of epileptiform discharges on scalp electroencephalogram and safe surgical resection challenging. We describe a case of a patient with glioblastoma multiforme presenting as dominant temporal lobe epilepsy. Seizures were manifest as episodes of speech arrest on a background of long-standing history of episodic speech difficulty and headache. In this case, recognizing a change in semiology allowed diagnosis of a high-grade glioma. Use of electrocorticography during surgical excision of the tumor guided safe maximal excision without damage to eloquent cortex and helped confirm the diagnosis of brain tumor-related epilepsy.

Original languageEnglish (US)
Pages (from-to)96-99
Number of pages4
JournalEpilepsy and Behavior Case Reports
StatePublished - 2017


  • All epilepsy/seizures
  • Intracranial electrodes
  • MRS
  • Multiple sclerosis
  • Primary brain tumor

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience


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