Osteoporosis and the risk of hip fracture

L. Joseph Melton, Heinz W. Wahner, Linda S. Richelson, W. Michael O'fallon, B. Lawrence Riggs

Research output: Contribution to journalArticlepeer-review

251 Scopus citations


The incidence of cervical and intertrochanteilc proximal femur fractures at various levels of cervical and intertrochanteric bone mineral density, respectively, was estimated by using population-based data from ongoing studies of osteoporosis and fractures among women residing in Rochester, Minnesota. Hip fractures were uncommon among women with femoral bone density ≥1.O g/cm2 but their frequency increased as bone density declined below that point at both ternoral sites. The incidence of cervical femur fractures was estimated at 8.3 per 1,000 person-years among women with cervical bone density <0.6 g/cm2 while the estimated incidence of intertrochanterlc femur fractures reached 16.6 per 1,000 person-years among those with intertrochanteric bone density <0.6 g/cm2 This new approach to the assessment of fracture risk from bone mineral density measurements indicates that osteoporosis is an important underlying cause of hip fractures.

Original languageEnglish (US)
Pages (from-to)254-261
Number of pages8
JournalAmerican journal of epidemiology
Issue number2
StatePublished - Aug 1986


  • Hip fractures
  • Osteoporosis

ASJC Scopus subject areas

  • Epidemiology


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