Optical Coherence Angiographic Demonstration of Retinal Changes From Chronic Optic Neuropathies

John J. Chen, Jackson E. AbouChehade, Raymond Iezzi, Jacqueline A. Leavitt, Randy H. Kardon

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


Glaucoma causes a decrease in peripapillary perfused capillary density on optical coherence tomography (OCT) angiography. However, other chronic optic neuropathies have not been explored with OCT angiography to see if these changes were specific to glaucoma. The authors evaluated OCT angiography in 10 patients who suffered various kinds of chronic optic neuropathies, including optic neuritis and ischaemic optic neuropathy, and found that all optic neuropathies showed a decrease in peripapillary vessel density on OCT angiography, regardless of the aetiology of the optic neuropathy. The peripapillary vessel loss on OCT angiography correlated well with the areas of retinal nerve fibre layer thinning seen on OCT.

Original languageEnglish (US)
Pages (from-to)76-83
Number of pages8
Issue number2
StatePublished - Mar 4 2017


  • OCT angiography
  • optic neuropathy
  • peripapillary capillaries

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology


Dive into the research topics of 'Optical Coherence Angiographic Demonstration of Retinal Changes From Chronic Optic Neuropathies'. Together they form a unique fingerprint.

Cite this