Oncologic emergencies: Diagnosis and treatment

Thorvardur R. Halfdanarson, William J. Hogan, Timothy J. Moynihan

Research output: Contribution to journalArticlepeer-review

67 Scopus citations


Patients with malignancies are subject to developing a unique set of complications that require emergent evaluation and treatment. With the increasing incidence of cancer in the general population and improved survival, these emergencies will be more frequently encountered. Physicians must be able to recognize these conditions and institute appropriate therapy after a focused initial evaluation. The approach to definitive therapy is commonly multidisciplinary, involving surgeons, radiation oncologists, medical oncologists, and other medical specialists. Prompt interventions can be lifesaving and may spare patients considerate morbidity and pain. In this review, we discuss the diagnosis of and initial therapy for common emergencies in hematology and oncology.

Original languageEnglish (US)
Pages (from-to)835-848
Number of pages14
JournalMayo Clinic proceedings
Issue number6
StatePublished - Jun 2006


  • CT = computed tomography
  • MRI = magnetic resonance imaging
  • MSCC = malignant spinal cord compression
  • PTH = parathyroid hormone
  • PTHrP = PTH-related protein
  • SVCS = superior vena cava syndrome
  • TLS = tumor lysis syndrome

ASJC Scopus subject areas

  • Medicine(all)


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