TY - JOUR
T1 - Olfaction in the elderly
T2 - A cross-sectional analysis comparing Parkinson's disease with controls and other disorders
AU - McKinnon, Jonathan
AU - Evidente, Virgilio
AU - Driver-Dunckley, Erika
AU - Premkumar, Ashvini
AU - Hentz, Joseph
AU - Shill, Holly
AU - Sabbagh, Marwan
AU - Caviness, John
AU - Connor, Donald
AU - Adler, Charles
PY - 2010
Y1 - 2010
N2 - Olfactory dysfunction in Parkinson's disease (PD) is an association that has been well documented in the medical literature, although the underlying pathophysiologic mechanism has not been clearly elucidated. In the Sun Health Research Institute Brain and Body Donation Program, subjects were tested for olfactory function. Olfaction was impaired in subjects with clinically probable PD but not those with essential tremor (ET), restless legs syndrome (RLS), or mild cognitive impairment. In the elderly control population there were no differences between genders and the UPSIT score decreased by 3.2 points per decade. These data confirm previous findings in PD, ET, and RLS, and expand the data for an elderly control population.
AB - Olfactory dysfunction in Parkinson's disease (PD) is an association that has been well documented in the medical literature, although the underlying pathophysiologic mechanism has not been clearly elucidated. In the Sun Health Research Institute Brain and Body Donation Program, subjects were tested for olfactory function. Olfaction was impaired in subjects with clinically probable PD but not those with essential tremor (ET), restless legs syndrome (RLS), or mild cognitive impairment. In the elderly control population there were no differences between genders and the UPSIT score decreased by 3.2 points per decade. These data confirm previous findings in PD, ET, and RLS, and expand the data for an elderly control population.
KW - Mild cognitive impairment
KW - Olfaction
KW - Parkinson
KW - Smell
UR - http://www.scopus.com/inward/record.url?scp=76749139049&partnerID=8YFLogxK
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U2 - 10.3109/00207450903428954
DO - 10.3109/00207450903428954
M3 - Article
C2 - 20128670
AN - SCOPUS:76749139049
SN - 0020-7454
VL - 120
SP - 36
EP - 39
JO - International Journal of Neuroscience
JF - International Journal of Neuroscience
IS - 1
ER -