Obstructive sleep apnea and vascular disease

Paola Lanfranchi, Virend K. Somers

Research output: Contribution to journalArticlepeer-review

97 Scopus citations


There is emerging evidence linking obstructive sleep apnea (OSA) to vascular disease, including hypertension. This relationship may be independent of co-morbidity, such as obesity. Even apparently healthy OSA patients have evidence of subtle functional vascular abnormalities that are known to occur in patients with hypertension and atherosclerosis. Untreated OSA may possibly contribute to the initiation and/or progression of pathophysiologic mechanisms involved in hypertension, heart failure, cardiac ischemia and stroke. This brief commentary will examine the evidence and mechanisms linking OSA to vascular disease.

Original languageEnglish (US)
Pages (from-to)315-319
Number of pages5
JournalRespiratory Research
Issue number6
StatePublished - 2001


  • Cardiovascular risk
  • Hypertension
  • Sleep apnea
  • Sympathetic nervous system
  • Vascular disease

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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