TY - JOUR
T1 - Nutritional Deficiencies in Celiac Disease
AU - Barton, Susan H.
AU - Kelly, Darlene G.
AU - Murray, Joseph A.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007/3
Y1 - 2007/3
N2 - Celiac disease is characterized by small bowel enteropathy, precipitated in genetically susceptible individuals by the ingestion of "gluten," which is a term used to encompass the storage proteins of wheat, rye, and barley. Although the intestine heals with removal of gluten from the diet, the intolerance is permanent and the damage recurs if gluten is reintroduced. This damage causes a wide variety of consequence including maldigestion and malabsorption, resulting in the characteristic, although not universal, features of malnutrition. This article examines recent advances in the understanding of the spectrum of celiac disease, illustrates the impact of celiac disease on nutrition, and describes approaches to the management of the disease.
AB - Celiac disease is characterized by small bowel enteropathy, precipitated in genetically susceptible individuals by the ingestion of "gluten," which is a term used to encompass the storage proteins of wheat, rye, and barley. Although the intestine heals with removal of gluten from the diet, the intolerance is permanent and the damage recurs if gluten is reintroduced. This damage causes a wide variety of consequence including maldigestion and malabsorption, resulting in the characteristic, although not universal, features of malnutrition. This article examines recent advances in the understanding of the spectrum of celiac disease, illustrates the impact of celiac disease on nutrition, and describes approaches to the management of the disease.
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U2 - 10.1016/j.gtc.2007.01.006
DO - 10.1016/j.gtc.2007.01.006
M3 - Review article
C2 - 17472877
AN - SCOPUS:34247540825
SN - 0889-8553
VL - 36
SP - 93
EP - 108
JO - Gastroenterology Clinics of North America
JF - Gastroenterology Clinics of North America
IS - 1
ER -