@article{72d216fd55434232ab04fc3b0dc2e5ce,
title = "Numb chin syndrome",
abstract = "“Numb chin syndrome” (NCS) refers to new-onset numbness of the lower lip and chin within the distribution of the mental or inferior alveolar nerves. While this focal numbness may be downplayed or even overlooked by patients and clinicians, in the right clinical scenario this may be the presenting symptom of an underlying malignancy. In the absence of any obvious, temporally related dental cause, there are certain conditions that clinicians should consider including orofacial and systemic malignancies as well as several inflammatory disorders. Thorough diagnostic evaluation should always be performed when no clear cause is evident. This paper will discuss the differential, recommended evaluations, and the prognosis, for a patient presenting with NCS.",
keywords = "Numb chin syndrome, Secondary headache, Sensory disturbance, Trigeminal neuropathy",
author = "Smith, {Ryan M.} and Anhar Hassan and Robertson, {Carrie E.}",
note = "Funding Information: 7-6 1-6 days for six untreated control dogs. These observations are in contrast to a report showing decreased immune reactivity to an allografted tumour after L-aspara-ginase treatment.26 Possibly the tumour-allograft system is not analogous to the skin or solid-organ graft system, since even a slight immunosuppression, as seen with some of our animals, would be enough to allow progressive growth of the tumour. Apparently the immunosuppressive effects of L-asparaginase (even in excessive doses 24) on cellular im- munity is at best minimal. The observations reported here are not as impressive as those of Shons et al.,21 who demonstrated prolonged survival of skin grafts in rabbits after the injection of L-asparaginase. The L-asparaginase was a gift from Merck Sharp and Dohme. This work was supported in part by the Life Insurance Medical Research Fund, the American Cancer Society, Inc., and a U.S.P.H.S. general research support grant. Departments of Anatomy and The Ohio Medicine,State University College of Medicine, Columbus, Ohio 43210. Publisher Copyright: {\textcopyright} 2015, Springer Science+Business Media New York.",
year = "2015",
month = sep,
day = "28",
doi = "10.1007/s11916-015-0515-y",
language = "English (US)",
volume = "19",
journal = "Current pain and headache reports",
issn = "1531-3433",
publisher = "Current Science, Inc.",
number = "9",
}