Normal-Weight Obesity: Implications for Cardiovascular Health

Nathalie Jean, Virend K. Somers, Ondrej Sochor, Jose Medina-Inojosa, Ernesto M. Llano, Francisco Lopez-Jimenez

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations


We sought to review the epidemiological features and clinical implications of normal-weight obesity. The concept of normal-weight obesity has been recently reported as an important risk factor for cardiovascular disease, metabolic dysregulation, and poor functional outcomes. However, in clinical practice, normal-weight obesity is not commonly recognized. In this review, we examine the clinical significance and important epidemiological outcomes of normal-weight obesity and describe other variants of adiposity and adiposity-related metabolic status. The incorporation of measures of body fat content and distribution in the clinical setting could allow more accurate identification of adiposity-related long-term risk. This could in turn lead to early lifestyle changes and behavioral modifications that are essential to the treatment of obesity.

Original languageEnglish (US)
Article number464
Pages (from-to)1-8
Number of pages8
JournalCurrent atherosclerosis reports
Issue number12
StatePublished - Dec 2014


  • Adiposity
  • Body mass index
  • Cardiovascular diseases
  • Cardiovascular mortality
  • Central obesity
  • Central obesity
  • Metabolic syndrome
  • Normal-weight obesity
  • Obesity
  • Sarcopenic obesity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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