Nonconvulsive status epilepticus secondary to acute porphyria crisis

Sara Dawit, Shubhang K. Bhatt, Devika M. Das, Andrew R. Pines, Harn J. Shiue, Brent P. Goodman, Joseph F. Drazkowski, Joseph I. Sirven

Research output: Contribution to journalArticlepeer-review


Both variegate and acute intermittent porphyria can manifest with various neurological symptoms. Although acute symptomatic seizures have been previously described, they are typically tonic–clonic and focal impaired awareness seizures. Convulsive status epilepticus and epilepsia partialis continua are rare and have been described on a case report basis. To our knowledge, there are no previously reported cases describing non-convulsive status epilepticus (NCSE) with electroencephalogram (EEG) documentation in the setting of acute porphyria crisis. We report a unique presentation of NCSE, which resolved after administering levetiracetam in a patient with variegate porphyria, without a known seizure disorder.

Original languageEnglish (US)
Pages (from-to)43-46
Number of pages4
JournalEpilepsy and Behavior Case Reports
StatePublished - Jan 1 2019


  • Acute porphyria crisis
  • Anticonvulsant medication
  • Electroencephalogram
  • Non-convulsive status epilepticus
  • Variegate porphyria

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience


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