Abstract
Emerging evidence supports that the entity known as idiopathic nodular glomerulosclerosis is not idiopathic. A strong causative association with longstanding cigarette smoking and hypertension has been identified. Morphologically, smoking-associated nodular glomerulosclerosis closely resembles diabetic nephropathy. The potential roles of advanced glycation end products, oxidative stress, angiogenesis, and hemodynamic perturbations are explored.
Original language | English (US) |
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Pages (from-to) | 2032-2036 |
Number of pages | 5 |
Journal | Journal of the American Society of Nephrology |
Volume | 18 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2007 |
ASJC Scopus subject areas
- Nephrology