New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities

A. Balkan; B. Tozkoparan; M. Ertan; Y. Sara; N. Ertekin

New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities

A. Balkan, B. Tozkoparan, M. Ertan, Y. Sara, N. Ertekin

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Abstract

The synthesis of a series of thiazolo[3,2-a]pyrimidine derivatives were described. The structures of the compounds were elucidated by IR, ¹H-NMR, ¹³C and elementary analysis. The compounds were evaluated for their calcium antagonistic activities using nifedipine as standart compound. All of the compounds were found to be less potent than nifedipine.

Original language	English (US)
Pages (from-to)	648-652
Number of pages	5
Journal	Bollettino Chimico Farmaceutico
Volume	135
Issue number	11
State	Published - Dec 1 1996

Keywords

Calcium antagonistic activities
Syntheis
Thiazolo[3,2-a]pyrimidines

ASJC Scopus subject areas

Molecular Medicine

Cite this

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title = "New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities",

abstract = "The synthesis of a series of thiazolo[3,2-a]pyrimidine derivatives were described. The structures of the compounds were elucidated by IR, 1H-NMR, 13C and elementary analysis. The compounds were evaluated for their calcium antagonistic activities using nifedipine as standart compound. All of the compounds were found to be less potent than nifedipine.",

keywords = "Calcium antagonistic activities, Syntheis, Thiazolo[3,2-a]pyrimidines",

author = "A. Balkan and B. Tozkoparan and M. Ertan and Y. Sara and N. Ertekin",

year = "1996",

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T1 - New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities

AU - Balkan, A.

AU - Tozkoparan, B.

AU - Ertan, M.

AU - Sara, Y.

AU - Ertekin, N.

PY - 1996/12/1

Y1 - 1996/12/1

N2 - The synthesis of a series of thiazolo[3,2-a]pyrimidine derivatives were described. The structures of the compounds were elucidated by IR, 1H-NMR, 13C and elementary analysis. The compounds were evaluated for their calcium antagonistic activities using nifedipine as standart compound. All of the compounds were found to be less potent than nifedipine.

AB - The synthesis of a series of thiazolo[3,2-a]pyrimidine derivatives were described. The structures of the compounds were elucidated by IR, 1H-NMR, 13C and elementary analysis. The compounds were evaluated for their calcium antagonistic activities using nifedipine as standart compound. All of the compounds were found to be less potent than nifedipine.

KW - Calcium antagonistic activities

KW - Syntheis

KW - Thiazolo[3,2-a]pyrimidines

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M3 - Article

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AN - SCOPUS:0030390606

SN - 0006-6648

VL - 135

SP - 648

EP - 652

JO - Bollettino Chimico Farmaceutico

JF - Bollettino Chimico Farmaceutico

IS - 11

ER -

New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities

Abstract

Keywords

ASJC Scopus subject areas

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