New directions in the epidemiology of uterine fibroids

Shannon K. Laughlin, Jane C. Schroeder, Donna Day Baird

Research output: Contribution to journalReview articlepeer-review

149 Scopus citations


Although uterine leiomyomata (fibroids) have been the leading indication for hysterectomy in the United States for decades, the epidemiological data on fibroid prevalence and risk factors are limited. Given the hormonal dependence of fibroids, most earlier studies focused on reproductive or hormonal factors. Recent analyses have extended that focus to other areas. We present previously unpublished data on the association between reproductive tract infections and fibroids that highlight the need for more detailed studies. Our review suggests that metabolic, dietary, stress, and environmental factors may also play a role in fibroid development.

Original languageEnglish (US)
Pages (from-to)204-217
Number of pages14
JournalSeminars in Reproductive Medicine
Issue number3
StatePublished - 2010


  • Diet
  • Environment
  • Epidemiology
  • Metabolic factors
  • Reproductive tract infection
  • Sexually transmitted disease
  • Uterine leiomyoma

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Reproductive Medicine
  • Endocrinology
  • Obstetrics and Gynecology
  • Physiology (medical)


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