New anticoagulant and antiplatelet agents: A primer for the gastroenterologist

Todd H. Baron, Patrick S. Kamath, Robert D. McBane

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


A large number of patients worldwide receive anticoagulant and antiplatelet agents, collectively known as antithrombotic agents. Several new anticoagulants and antiplatelet agents recently were approved for use. Gastroenterologists may be unfamiliar with the mechanism of action, indications for use, and pharmacokinetics of these newer drugs. In patients undergoing elective and urgent endoscopic procedures, clinicians must be familiar with these medications to optimize outcomes. When the decision is made to continue the newer antithrombotic agents for elective procedures, the clinician must understand the risk that these agents may impart on procedural-induced bleeding. Finally, it is important to understand how to manage these agents in the presence of acute gastrointestinal bleeding. In this article the use of newer antithrombotic agents is reviewed.

Original languageEnglish (US)
Pages (from-to)187-195
Number of pages9
JournalClinical Gastroenterology and Hepatology
Issue number2
StatePublished - Feb 2014


  • Anticoagulants/Administration and dosage
  • Atrial fibrillation
  • Drug administration schedule
  • Drug monitoring
  • Endoscopy
  • Gastrointestinal
  • Thrombosis/Drug therapy

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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