Neurotensin agonists: Possible drugs for treatment of psychostimulant abuse

Elliott Richelson, Mona Boules, Paul Fredrickson

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Although many neuropeptides have been implicated in the pathophysiology of psychostimulant abuse, the tridecapeptide neurotensin holds a prominent position in this field due to the compelling literature on this peptide and psychostimulants. These data strongly support the hypothesis that a neurotensin agonist will be clinically useful to treat the abuse of psychostimulants, including nicotine. This paper reviews the evidence for a role for neurotensin in stimulant abuse and for a neurotensin agonist for its treatment.

Original languageEnglish (US)
Pages (from-to)679-690
Number of pages12
JournalLife Sciences
Issue number6
StatePublished - Jun 27 2003

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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