Neurological complications of plasma cell disorders

Jan Drappatz, Kurt A. Jaeckle

Research output: Chapter in Book/Report/Conference proceedingChapter


Plasma cell disorders include monoclonal gammopathies of unknown significance, multiple myeloma, plasmacytoma, Waldenstrom's macroglobulinemia, and amyloidosis. This group of neoplastic diseases involves proliferation of a single clone of plasma cells, producing a monoclonal immunoglobulin protein or immunoglobulin fragment (M protein) that can be identified as a spike on electrophoresis of serum or urine. Plasma cell disorders are associated with a wide spectrum of neurological complications. The pathophysiology, diagnosis, and management of these neurological complications are the subject of this review.

Original languageEnglish (US)
Title of host publicationLymphoma and Leukemia of the Nervous System
PublisherSpringer New York
Number of pages14
ISBN (Electronic)9781441976680
ISBN (Print)9781441976673
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • General Medicine


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