TY - JOUR
T1 - Neurological Complications in Patients with Heart Transplantation
AU - Sakusic, Amra
AU - Rabinstein, Alejandro A.
N1 - Publisher Copyright:
© 2021 American Institute of Physics Inc.. All rights reserved.
PY - 2021/8/1
Y1 - 2021/8/1
N2 - Neurological complications after heart transplantation are common and include cerebrovascular events (ischemic strokes, hemorrhagic strokes, and transient ischemic attacks), seizures, encephalopathy, central nervous system (CNS) infections, malignancies, and peripheral nervous system complications. Although most neurological complications are transient, strokes and CNS infections can result in high mortality and morbidity. Early recognition and timely management of these serious complications are crucial to improve survival and recovery. Diagnosing CNS infections can be challenging because their clinical presentation can be subtle in the setting of immunosuppression. Immunosuppressive medications themselves can cause a broad spectrum of neurological complications including seizures and posterior reversible encephalopathy syndrome. This article provides a review of the diagnosis and management of neurological complications after cardiac transplantation.
AB - Neurological complications after heart transplantation are common and include cerebrovascular events (ischemic strokes, hemorrhagic strokes, and transient ischemic attacks), seizures, encephalopathy, central nervous system (CNS) infections, malignancies, and peripheral nervous system complications. Although most neurological complications are transient, strokes and CNS infections can result in high mortality and morbidity. Early recognition and timely management of these serious complications are crucial to improve survival and recovery. Diagnosing CNS infections can be challenging because their clinical presentation can be subtle in the setting of immunosuppression. Immunosuppressive medications themselves can cause a broad spectrum of neurological complications including seizures and posterior reversible encephalopathy syndrome. This article provides a review of the diagnosis and management of neurological complications after cardiac transplantation.
KW - central nervous system infections
KW - cerebrovascular events
KW - heart transplantation
KW - neurological complications
KW - seizures
UR - http://www.scopus.com/inward/record.url?scp=85104367272&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85104367272&partnerID=8YFLogxK
U2 - 10.1055/s-0041-1726285
DO - 10.1055/s-0041-1726285
M3 - Article
C2 - 33851398
AN - SCOPUS:85104367272
SN - 0271-8235
VL - 41
SP - 447
EP - 452
JO - Seminars in Neurology
JF - Seminars in Neurology
IS - 4
ER -