Neurohumoral and renal mechanisms in heart failure

J. Winaver, J. C. Burnett

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


This review has importantly established the continued view that the syndrome of CHF is partly mediated by adaptive neurohumoral and renal mechanism. Continuing work is required, not only to further understand the role of these mechanisms in the pathophysiology of heart failure but also to develop appropriate therapeutic strategies for attenuating the vasoconstrictor mechanism and promoting the vasodilator-natriuretic systems in the regulation of cardiovascular homeostasis.

Original languageEnglish (US)
Pages (from-to)278-284
Number of pages7
JournalCurrent opinion in cardiology
Issue number3
StatePublished - 1990

ASJC Scopus subject areas

  • General Medicine


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