TY - JOUR
T1 - Neural control of canine small intestinal interdigestive myoelectric complexes
AU - Heppell, J.
AU - Kelly, K. A.
AU - Sarr, M. G.
PY - 1983
Y1 - 1983
N2 - Our aim was to determine the role of the extrinsic and intrinsic nerves in the regulation of the small intestinal interdigestive myoelectric complex (IMC). In five dogs, the extrinsic nerves of the jejunoileum were divided, but the bowel was left in situ with its wall intact. After recovery, IMCs were detected in the duodenum (mean IMC period ± SE = 188 ± 19 min), from where most migrated distally into and through the jejunum (84%). In addition, extra IMCs appeared in the jejunum. Thus, the mean period of the IMCs in the jejunum (134 ± 10 min) was shorter than in the duodenum (P < 0.05). In contrast, after enteric transection and reanastomosis at the ligament of Treitz and at a site 75 cm distal to the ligament, fewer duodenal IMCs migrated into the jejunum (only 61%). However, extra MICs still arose in the jejunum, so that the mean period of IMCs in the jejunum (111 ± 5 min) was now similar to that in the duodenum (128 ± 4 min, P > 0.05). Our data were consistent with the hypothesis that extrinsic nerves regulate the frequency of the small intestinal IMCs, while an intact enteric wall aids in their distal propagation.
AB - Our aim was to determine the role of the extrinsic and intrinsic nerves in the regulation of the small intestinal interdigestive myoelectric complex (IMC). In five dogs, the extrinsic nerves of the jejunoileum were divided, but the bowel was left in situ with its wall intact. After recovery, IMCs were detected in the duodenum (mean IMC period ± SE = 188 ± 19 min), from where most migrated distally into and through the jejunum (84%). In addition, extra IMCs appeared in the jejunum. Thus, the mean period of the IMCs in the jejunum (134 ± 10 min) was shorter than in the duodenum (P < 0.05). In contrast, after enteric transection and reanastomosis at the ligament of Treitz and at a site 75 cm distal to the ligament, fewer duodenal IMCs migrated into the jejunum (only 61%). However, extra MICs still arose in the jejunum, so that the mean period of IMCs in the jejunum (111 ± 5 min) was now similar to that in the duodenum (128 ± 4 min, P > 0.05). Our data were consistent with the hypothesis that extrinsic nerves regulate the frequency of the small intestinal IMCs, while an intact enteric wall aids in their distal propagation.
UR - http://www.scopus.com/inward/record.url?scp=0020670694&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020670694&partnerID=8YFLogxK
U2 - 10.1152/ajpgi.1983.244.1.g95
DO - 10.1152/ajpgi.1983.244.1.g95
M3 - Article
C2 - 6849397
AN - SCOPUS:0020670694
SN - 0193-1857
VL - 7
SP - G95-G100
JO - American Journal of Physiology - Gastrointestinal and Liver Physiology
JF - American Journal of Physiology - Gastrointestinal and Liver Physiology
IS - 1
ER -