Nerve Tubes for Peripheral Nerve Repair

Godard C.W. de Ruiter, Robert J. Spinner, Michael J. Yaszemski, Anthony J. Windebank, Martijn J.A. Malessy

Research output: Contribution to journalReview articlepeer-review

52 Scopus citations


The concept of the nerve tube has been a major topic of research in the field of peripheral nerve regeneration for more than 25 years. The first nerve tubes are currently available for clinical use. This article gives an overview of the experimental and clinical data on nerve tubes for peripheral nerve repair and critically analyzes the data on which the step from laboratory to clinical use is based. In addition, it briefly discusses the different modifications to the common single lumen nerve tubes that may improve the results of generation.

Original languageEnglish (US)
Pages (from-to)91-105
Number of pages15
JournalNeurosurgery clinics of North America
Issue number1
StatePublished - Jan 2009


  • Animal models
  • Clinical nerve repair
  • Evaluation methods
  • Modified nerve tubes
  • Nerve conduits
  • Nerve guides
  • Nerve tubes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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