Necrotizing fasciitis of the face: A life-threatening condition

Ilenia Pepe, Lucio Lo Russo, Valentina Cannone, Anna Giammanco, Fortunato Sorrentino, Domenico Ciavarella, Giuseppina Campisi

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Necrotizing fasciitis (NF) is a highly aggressive infectious process, polymicrobial in nature, involving soft tissues with a high risk of rapid spread through superficial and deep fascial planes and muscular layers. Cervical NF is quite rare, is mostly of odontogenic origin, and may be complicated by descendant mediastinitis with a very high mortality rate. Systemic conditions impairing the patient's immune competence, such as diabetes, may play a predisposing role. An effective treatment strategy includes prompt diagnosis (clinical findings, local microbiological tests, blood culture and, if deemed necessary, histopathology), broad-spectrum antibiotic therapy as early as possible which should be later adjusted according to antibiogram results, stabilization of vital functions and, if possible, elimination/treatment of predisposing factors. This paper describes a complex and emblematic case.

Original languageEnglish (US)
Pages (from-to)358-362
Number of pages5
JournalAging Clinical and Experimental Research
Issue number4-5
StatePublished - 2009


  • Complications
  • Face
  • Infections
  • Neck
  • Necrotizing fasciitis

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology


Dive into the research topics of 'Necrotizing fasciitis of the face: A life-threatening condition'. Together they form a unique fingerprint.

Cite this