Myasthenia gravis in two cats

R. J. Indrieri, S. R. Creighton, E. H. Lambert, V. A. Lennon

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


A case of the autoimmune form of myasthenia gravis and a case of what is probably a congenital form of myasthenia gravis were diagnosed in 2 unrelated cats. Neuromuscular weakness exacerbated by exercise was a prominent feature in both cats. Weakness was eliminated temporarily by administration of anticholinesterase drugs. Serum autoantibodies to acetylcholine receptors of skeletal muscle were present in the 1st cat and were not detected in the 2nd cat. A characteristic decrement in the amplitude of the compound muscle action potential during repetitive stimulation of the motor nerve was elicited in the 2nd cat. There was marked electromyographic improvement in response to anticholinesterase drugs. Electromyography was not performed in the 1st cat.

Original languageEnglish (US)
Pages (from-to)57-60
Number of pages4
JournalJournal of the American Veterinary Medical Association
Issue number1
StatePublished - 1983

ASJC Scopus subject areas

  • General Veterinary


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