Muscle ultrasound

Sigrid Pillen, Andrea Boon, Nens Van Alfen

Research output: Chapter in Book/Report/Conference proceedingChapter

15 Scopus citations


Muscle ultrasound is an ideal imaging modality that allows for noninvasive, radiation-free point-of-care neuromuscular imaging. There are many potential applications of muscle ultrasound, including identification of abnormal muscle movements such as fasciculations, evaluation of muscle trauma, identification of physiologic parameters such as pennation angle, accurate performance of chemodenervation, and improved accuracy of challenging electrodiagnostic studies such as phrenic nerve conduction studies or needle electromyogram (EMG) of the diaphragm. Tissue Doppler imaging can be used to help identify inflammatory myopathies. With computer-assisted quantification, muscle ultrasound has high sensitivity and specificity in the diagnosis of pediatric neuromuscular disease and amyotrophic lateral sclerosis, and is a valuable addition to other diagnostic techniques for neuromuscular disease. When used as a first-line screening tool it can obviate the need for more invasive procedures such as EMG or muscle biopsy in certain patients. This chapter provides an overview of the fundamentals, clinical applications, and validation of muscle ultrasound for patients with neuromuscular disorders.

Original languageEnglish (US)
Title of host publicationNeuroimaging Part II, 2016
EditorsJoseph C. Masdeu, R. Gilberto Gonzalez
PublisherElsevier B.V.
Number of pages11
ISBN (Print)9780444534866
StatePublished - Dec 1 2016

Publication series

NameHandbook of Clinical Neurology
ISSN (Print)0072-9752
ISSN (Electronic)2212-4152


  • Doppler imaging
  • Heckmatt scale
  • congenital myopathy
  • dystrophy
  • echogenicity
  • fasciculations
  • motor neuron disease
  • muscle ultrasound
  • myositis
  • quantitative

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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