Multilocular renal cyst. A hamartoma with potential for neoplastic transformation?

M. E. Sherman, M. L. Silverman, K. Balogh, S. S.G. Tan

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Multilocular renal cyst is a pathologically distinctive lesion of uncertain pathogenesis that usually presents as a large abdominal mass in male infants or middle-aged women. We performed detailed light and electron microscopic studies of three nephrectomy specimens that contained multilocular cysts and attempted to correlate their morphology with various theories of pathogenesis. In one of our cases, a microscopic focus of clear cells that resembled renal cell adenocarcinoma was observed in the wall of one locule. Although such a finding has been reported previously, the lack of well-documented cases with metastases suggests that the prognosis for patients with this lesion remains uniformly excellent.

Original languageEnglish (US)
Pages (from-to)732-736
Number of pages5
JournalArchives of Pathology and Laboratory Medicine
Issue number8
StatePublished - 1987

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


Dive into the research topics of 'Multilocular renal cyst. A hamartoma with potential for neoplastic transformation?'. Together they form a unique fingerprint.

Cite this