Multi-energy CT with Triple X-ray Beams: A feasibility animal study

Liqiang Ren, Kishore Rajendran, Joel G. Fletcher, Thomas Allmendinger, Ahmed Halaweish, Bernhard Schmidt, Thomas Flohr, Cynthia H. McCollough, Lifeng Yu

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Energy-integrating-detector (EID)-based triple-beam multi-energy CT (TB-MECT) was recently implemented on a dual-source (DS) CT platform by mounting a z-axis split-filter (0.05 mm Au, 0.6 mm Sn) on one of the two tubes. The purpose of this work is to perform a feasibility animal study on this new MECT platform for a small bowel imaging task using two contrast agents, iodine and bismuth. Optimal triple-beam configurations, 70/Au140/Sn140 kV were determined in a phantom study for this task and applied in the animal study for best material decomposition imaging performance. The results demonstrated that the TB-MECT can successfully separate and quantify the two contrast agents from one single scan for the task of small bowel imaging.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2020
Subtitle of host publicationPhysics of Medical Imaging
EditorsGuang-Hong Chen, Hilde Bosmans
ISBN (Electronic)9781510633919
StatePublished - 2020
EventMedical Imaging 2020: Physics of Medical Imaging - Houston, United States
Duration: Feb 16 2020Feb 19 2020

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMedical Imaging 2020: Physics of Medical Imaging
Country/TerritoryUnited States


  • Material-specific Imaging
  • Multi-energy CT (MECT)
  • Multiple Contrast Agents

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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