Monoclonal gammopathy of undetermined significance

Robert A. Kyle, S Vincent Rajkumar

Research output: Chapter in Book/Report/Conference proceedingChapter


Monoclonal gammopathy of undetermined significance (MGUS) is defined by a monoclonal immunoglobulin in serum of <3 g/dL, fewer than 10% plasma cells in the bone marrow and no evidence of lytic bone lesions, anemia, hypercalcemia, or renal insufficiency related to the plasma cell proliferative process. More than 50% of patients with a monoclonal gammopathy at Mayo Clinic have MGUS. IgG is the most common type of M protein.

Original languageEnglish (US)
Title of host publicationMultiple Myeloma
Subtitle of host publicationTranslational and Emerging Therapies
PublisherCRC Press
Number of pages20
ISBN (Electronic)9781420045116
ISBN (Print)9781420045109
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Monoclonal gammopathy of undetermined significance'. Together they form a unique fingerprint.

Cite this