MitraClip Therapy for Mitral Regurgitation: Secondary Mitral Regurgitation

Ted Feldman, Arjun Mehta, Mayra Guerrero, Justin P. Levisay, Michael H. Salinger

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Therapy for mitral regurgitation (MR) has been synonymous with mitral valve surgery. Operative approaches for degenerative MR repair have been associated with excellent results, with durable long term outcomes. Surgery for functional MR has been less successful. MitraClip has shown promise for functional MR, especiall in patinets who are high risk for surgery. The aggregate of nonrandomized global experience with MitraClip in functional MR has been consistent in showing improvements in symptoms and left ventricular remodeling. It remains to be seen how MitraClip therapy will compare with best medical therapy. The COAPT trial will clarify this question.

Original languageEnglish (US)
Pages (from-to)83-91
Number of pages9
JournalInterventional Cardiology Clinics
Issue number1
StatePublished - Jan 2016


  • Functional mitral regurgitation
  • MitraClip
  • Mitral regurgitation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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