Microscopic Colitis, Collagenous and Lymphocytic

Amrit K. Kamboj, Darrell S. Pardi

Research output: Chapter in Book/Report/Conference proceedingChapter


Microscopic colitis is a chronic inflammatory disease of the colon characterized by chronic watery diarrhea. While the colonic mucosa appears grossly normal in microscopic colitis, the diagnosis is based on abnormal histologic features. There are two main subtypes, collagenous colitis and lymphocytic colitis, which have similar clinical features and therefore are differentiated histologically. In this article, we review the disease epidemiology, pathophysiology, clinical manifestations, and treatment options.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Gastroenterology, Second Edition
Number of pages8
ISBN (Electronic)9780128124604
StatePublished - Jan 1 2019


  • Bismuth subsalicylate
  • Budesonide
  • Celiac disease
  • Chronic diarrhea
  • Collagenous colitis
  • Functional diarrhea
  • Irritable bowel syndrome
  • Large intestine
  • Loperamide
  • Lymphocytic colitis
  • Microscopic colitis
  • Nonsteroidal antiinflammatory drugs
  • Proton pump inhibitors
  • Watery diarrhea

ASJC Scopus subject areas

  • General Medicine


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