Methods to assess potential reduced exposure products

Dorothy K. Hatsukami, Gary A. Giovino, Thomas Eissenberg, Pamela I. Clark, Deirdre Lawrence, Scott Leischow

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


The availability of tobacco products purported to reduce toxin exposure or potentially reduce health risks necessitates the development of methods and identification of biomarkers that can be used to assess these products. These assessments occur on multiple levels and stages, from identifying constituents in the tobacco products and smoke, to human exposure and health effects trials, to postmarketing surveillance. A conference of multidisciplinary experts was convened to present and discuss methods and biomarkers to assess these products and to consider the infrastructure necessary to facilitate the evaluation process. Although no currently available set of measures was thought to be sufficient for determining the relative health risk of potential reduced exposure products, this paper provides a blueprint for future research toward this end.

Original languageEnglish (US)
Pages (from-to)827-844
Number of pages18
JournalNicotine and Tobacco Research
Issue number6
StatePublished - Dec 2005

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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