Methicillin-resistant staphylococcus aureus infection and treatment options

Sarah J. Chalmers, Mark E. Wylam

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of infection worldwide, including a wide array of both hospital- and community-acquired infections—most commonly bacteremia, upper and lower respiratory tract infection, skin and soft-tissue infection, osteomyelitis, and septic arthritis. This chapter describes the epidemiology of MRSA infection, its ability to confer antibiotic resistance and produce a wide array of virulence factors, and its pivotal role in human infection, especially cystic fibrosis. It also provides an introduction to the strategies for treatment of both chronic and acute MRSA infections.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages229-251
Number of pages23
DOIs
StatePublished - 2020

Publication series

NameMethods in Molecular Biology
Volume2069
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Bacteremia
  • Community acquired
  • Hospital acquired
  • Lung infection
  • Methicillin-resistant Staphylococcus aureus

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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