Metabolic Liver Diseases

Maureen M.J. Guichelaar, Michael R. Charlton

Research output: Chapter in Book/Report/Conference proceedingChapter


Metabolic liver diseases can result into intra- and/or extrahepatic complications requiring orthotopic liver transplantation (OLT). Metabolic liver disease as a cause of OLT is proportionally more common in pediatric patients than adults. In adults the most common metabolic indications for OLT are NASH, alpha-1-antitrypsin deficiency, hemochromatosis and Wilson disease. NASH as an indication for OLT will increase in the future and is predicted to become the leading cause for OLT in the near future.

Original languageEnglish (US)
Title of host publicationMedical Care of the Liver Transplant Patient
Subtitle of host publication4th Edition
Number of pages13
ISBN (Print)9781444335910
StatePublished - Mar 28 2012


  • Alpha-1-antitrypsin deficiency
  • Hemochromatosis
  • M. Wilson
  • NASH

ASJC Scopus subject areas

  • Medicine(all)


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