Mesial Temporal Sclerosis After Posterior Reversible Encephalopathy Syndrome

Mariam S. Aboian, Mithri R. Junna, Karl N. Krecke, Elaine C. Wirrell

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Neither intrathecal methotrexate nor posterior reversible encephalopathy syndrome has previously been reported to result in mesial temporal sclerosis. Described here is the case of a boy with no risk factors for mesial temporal sclerosis who presented with posterior reversible encephalopathy syndrome and partial complex seizures 8 days after initiation of intrathecal methotrexate for treatment of Burkitt lymphoma, and who ultimately progressed to intractable temporal lobe epilepsy due to left mesial temporal sclerosis.

Original languageEnglish (US)
Pages (from-to)226-228
Number of pages3
JournalPediatric Neurology
Issue number3
StatePublished - Sep 2009

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology


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