Memory support system in spanish: A pilot study

Octavio A. Santos, Anapaula Rios-Rosales, Otto Pedraza, Caroline D. Bergeron, Melanie Chandler

Research output: Contribution to journalArticlepeer-review


Subjective cognitive decline (SCD) is prevalent in the general population, particularly among Hispanic adults. SCD increases the risk of mild cognitive impairment (MCI) and dementia. While non-pharmacologic interventions are recommended to mitigate cognitive decline and preserve daily function in SCD and MCI, such interventions are not readily available for Spanish-speaking Hispanic adults with SCD. This pilot study, preregistered at, aimed to develop a linguistically and culturally appropriate adaptation of an existing memory compensation intervention, the Memory Support System (MSS), from English to Spanish, and to gather data to assess its impact in this population. Twenty Spanish-speaking Hispanic adults with SCD and 16 support partners were recruited. Measures of treatment adherence, daily function, self-efficacy for memory, quality of life, mood, anxiety, and caregiver burden were assessed at baseline, treatment end, and 8-week follow-up. By treatment end, participants with SCD improved their general functional status, daily activities requiring organizational skills, and depression and anxiety symptoms. Partners reported improvement in anxiety by treatment end and in caregiver burden at follow-up. The MSS was successfully translated into Spanish and readily learned by participants with SCD and their partners. The MSS in Spanish may help with daily functioning and aspects of patient and family well-being.

Original languageEnglish (US)
Article number1379
JournalBrain Sciences
Issue number11
StatePublished - Nov 2021


  • Behavioral intervention
  • Cognitive rehabilitation
  • Functional ability
  • Subjective cognitive decline

ASJC Scopus subject areas

  • Neuroscience(all)


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