Membrane guanylyl cyclase receptors: an update

David L. Garbers, Ted D. Chrisman, Phi Wiegn, Takeshi Katafuchi, Joseph P. Albanesi, Vincent Bielinski, Barbara Barylko, Margaret M. Redfield, John C. Burnett

Research output: Contribution to journalReview articlepeer-review

92 Scopus citations


Recent studies have demonstrated key roles for several membrane guanylyl cyclase receptors in the regulation of cell hyperplasia, hypertrophy, migration and extracellular matrix production, all of which having an impact on clinically relevant diseases, including tissue remodeling after injury. Additionally, cell differentiation, and even tumor progression, can be profoundly influenced by one or more of these receptors. Some of these receptors also mediate important communication between the heart and intestine, and the kidney to regulate blood volume and Na+ balance.

Original languageEnglish (US)
Pages (from-to)251-258
Number of pages8
JournalTrends in Endocrinology and Metabolism
Issue number6
StatePublished - Aug 2006

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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