Medical and Endoscopic Management of Crohn Disease

Parakkal Deepak, Daniel R. Ludwig, Jeff L. Fidler, Flavius F. Guglielmo, David H. Bruining

Research output: Contribution to journalReview articlepeer-review


AbstractIn this review, through a series of questions and answers, we explore the current approach to classifying patients with Crohn disease into low-risk (mild-moderate) and high-risk (moderate-severe) categories with the recommended treatment approaches per guidelines from the International Organization for the Study of Inflammatory Bowel Diseases, American Gastroenterological Association, the American College of Gastroenterology, and the European Crohn's and Colitis Organization detailed here. The development pipeline of potential therapies is also summarized. We also review key information from magnetic resonance enterography and pelvis imaging studies that the abdominal radiologist can communicate to a multidisciplinary treatment team that includes gastroenterologists and colorectal surgeons, with a goal of achieving optimal patient outcomes. Lastly, endoscopic and radiological treatment targets in a treat-to-target approach in Crohn disease are explored.

Original languageEnglish (US)
Pages (from-to)43-61
Number of pages19
JournalTopics in Magnetic Resonance Imaging
Issue number1
StatePublished - Feb 1 2021


  • Crohn disease/complications
  • Crohn disease/diagnostic imaging
  • Crohn disease/therapy
  • magnetic resonance imaging/methods
  • severity of illness index

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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