Measurement of murine serum amyloid P component by rate nephelometry

Morie A. Gertz, Jean D. Sipe, Martha Skinner, Alan S. Cohen, Robert A. Kyle

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Murine serum amyloid P component (SAP) is an acute-phase protein that is increased 2-10-fold in concentration following appropriate inflammatory or infections stimuli. Previous studies of the acute-phase SAP response have employed quantitative immunoelectrophoresis or radioimmunoassay to measure SAP concentration. A rate nephelometric procedure has been developed which measures SAP concentration rapidly and with equivalent or greater precision than the previously applied techniques. This simple method will facilitate experimental and clinical studies of the acute-phase response.

Original languageEnglish (US)
Pages (from-to)173-180
Number of pages8
JournalJournal of Immunological Methods
Issue number2
StatePublished - Apr 27 1984


  • acute-phase response
  • nephelometry
  • serum amyloid P (SAP)

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


Dive into the research topics of 'Measurement of murine serum amyloid P component by rate nephelometry'. Together they form a unique fingerprint.

Cite this