Massive localised lymphoedema: Clinical presentation and MR imaging characteristics

Monica Khanna, Ali M. Naraghi, David Salonen, Rejpaul Bhumbra, Brendan C. Dickson, Mark J. Kransdorf, Lawrence M. White

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Three morbidly obese women were referred to us with suspected soft-tissue sarcomas. All lesions arose from the medial subcutaneous tissues of the thigh, and were shown to represent massive localised lymphoedema (MLL), a rare condition occurring in morbidly obese adults. MR imaging typically demonstrates a sharply demarcated, pedunculated mass consisting of fat partitioned by fibrous septae surrounded by a thickened dermis. There is oedema both within the mass and tracking along the subcutaneous septae in a "lace-like" fashion outwards from the pedicle, outlining large lobules of fat. Minimal enhancement is observed within the dermis of the lesion following intravenous gadolinium administration. Obesity is a growing problem that is likely to result in an increase in the prevalence of this condition; therefore, familiarity with the radiological appearance is important in establishing a correct diagnosis in this condition that may mimic a soft-tissue sarcoma.

Original languageEnglish (US)
Pages (from-to)647-652
Number of pages6
JournalSkeletal Radiology
Issue number5
StatePublished - May 1 2011

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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