Mania and hypomania following traumatic brain injury in children and adolescents

Jeffrey E. Max, Wilbur L. Smith, Yutaka Sato, Philip J. Mattheis, Donald A. Robin, Julie A.G. Stierwalt, Scott D. Lindgren, Carlos Castillo

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


The first series of secondary mania reported in children and adolescents is described. Four of 50 subjects (8%) from a prospective study of consecutive children hospitalized following traumatic brain injury developed mania or hypomania. The phenomenology is discussed regarding the overlapping diagnoses of mania, attention-deficit hyperactivity disorder, organic personality syndrome and the 'frontal lobe syndrome'. Severity of injury, lesion location and family history of major mood disorder may be implicated in the etiology of secondary mania. Lengthy episodes and similar frequency of irritability and elation may be characteristic.

Original languageEnglish (US)
Pages (from-to)119-126
Number of pages8
Issue number2
StatePublished - 1997


  • Children and adolescents
  • Secondary mania
  • Traumatic brain injury

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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