Managing Innovation to Maximize Value Along the Discovery-Translation-Application Continuum

S. A. Waldman, A. Terzic

Research output: Contribution to journalEditorialpeer-review

6 Scopus citations


Success in pharmaceutical development led to a record 51 drugs approved in the past year, surpassing every previous year since 1950. Technology innovation enabled identification and exploitation of increasingly precise disease targets ensuring next generation diagnostic and therapeutic products for patient management. The expanding biopharmaceutical portfolio stands, however, in contradistinction to the unsustainable costs that reflect remarkable challenges of clinical development programs. This annual Therapeutic Innovations issue juxtaposes advances in translating molecular breakthroughs into transformative therapies with essential considerations for lowering attrition and improving the cost-effectiveness of the drug-development paradigm. Realizing the discovery-translation-application continuum mandates a congruent approval, adoption, and access triad.

Original languageEnglish (US)
Pages (from-to)8-12
Number of pages5
JournalClinical pharmacology and therapeutics
Issue number1
StatePublished - Jan 1 2017

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)


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