Management of germ cell tumors

Manish Kohli; Ben Y. Zhang; Brian A. Costello

doi:10.1007/978-3-662-53775-6_5

Management of germ cell tumors

Manish Kohli, Ben Y. Zhang, Brian A. Costello

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Germ cell tumors typically present in younger age populations and are known to be extremely sensitive to chemotherapy and radiation. As a result of this, remarkable progress has been achieved for offering a high degree of curative outcomes for these tumor types using a stepwise, stage-specific integration of surgery, chemotherapy, and radiation. A common theme in the treatment paradigm is to offer high cure rates without compromising on fertility in this typically young population of patients. This chapter will summarize the management of germ cell tumors using testicular germ cell tumors as the prototype example since it has been studied extensively. Principles of management of malignant ovarian germ cell tumors are currently based on treatments that have evolved from the study of testicular cancer and also offer a high rate of cure.

Original language	English (US)
Title of host publication	Pathology and Biology of Human Germ Cell Tumors
Publisher	Springer Berlin Heidelberg
Pages	181-194
Number of pages	14
ISBN (Electronic)	9783662537756
ISBN (Print)	9783662537732
DOIs	https://doi.org/10.1007/978-3-662-53775-6_5
State	Published - Jan 1 2017

Keywords

Germ cell tumor
Non-seminoma
Ovarian
Seminoma
Treatment

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-662-53775-6_5

Cite this

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AU - Zhang, Ben Y.

AU - Costello, Brian A.

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AB - Germ cell tumors typically present in younger age populations and are known to be extremely sensitive to chemotherapy and radiation. As a result of this, remarkable progress has been achieved for offering a high degree of curative outcomes for these tumor types using a stepwise, stage-specific integration of surgery, chemotherapy, and radiation. A common theme in the treatment paradigm is to offer high cure rates without compromising on fertility in this typically young population of patients. This chapter will summarize the management of germ cell tumors using testicular germ cell tumors as the prototype example since it has been studied extensively. Principles of management of malignant ovarian germ cell tumors are currently based on treatments that have evolved from the study of testicular cancer and also offer a high rate of cure.

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KW - Seminoma

KW - Treatment

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Management of germ cell tumors

Abstract

Keywords

ASJC Scopus subject areas

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