The lung is a structurally hierarchical, highly complex organ in which form and function are determined by a delicate balance between intrinsic and extrinsic mechanical forces. Magnetic resonance elastograpy (MRE) therefore provides a unique opportunity to non-invasively study this balance and its affect on parenchymal stiffness in both normal and diseased lungs. However, lung MRE is particularly challenging due to factors such as low signal-to-noise, organ motion, and the ability to non-invasively generate shear waves with the lung. This chapter describes the challenges, recent advances, and the potential for MRE as a new non-invasive diagnostic probe of the mechanical properties of the lung.
|Original language||English (US)|
|Title of host publication||Magnetic Resonance Elastography|
|Publisher||Springer New York|
|Number of pages||10|
|ISBN (Print)||1493915746, 9781493915743|
|State||Published - Jul 1 2014|
ASJC Scopus subject areas